CAS#2803881-11-8|(2- (2,6-dioxopiperidin-3-yl) -3-oxoisoindolin-5-yl) methyl (2-fluoro-5- (trifluormethoxy) phenyl) carbamat

Produktnavn	(2- (2,6-dioxopiperidin-3-yl) -3-oxoisoindolin-5-yl) methyl (2-fluoro-5- (trifluormethoxy) phenyl) carbamat	Strukturformel	​
CAS Nej.	2803881-11-8	Molekylvægt	495.38
Udseende	Solid	Kogepunkt	644,0 ± 55,0 grad (forudsagt)
Assay	99%	Pakke	5 mg; 10 mg
Formel	C22H17F4N3O6

 

Anvendelse

 

• MRT-2359 is a potent, orally active and selective GSPT1 depressant (IC50: >30 nm og<300 nM) that specifically induces apoptosis dependent on protein translation. MRT-2359 exhibits significant and preferred anti-proliferative activity in a variety of cancer cell lines, especially MYC-driven cell lines, such as non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) with high expression of N-Myc or L-Myc. MRT-2359 inhibits the growth of drug-resistant NSCLC and SCLC cells, making it suitable for cancer research[1][2][3][4][5].

 

Forsendelse

 

 

 

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